In order to take into account the size of the subject it is better to use indexed values for cardiac output (CO) and systemic vascular resistance (SVR), since a large subject will have a higher CO but lower SVR than a small subject (a small subject has small arteries which offer a greater resistance). Body surface area (BSA) is used as a measure of subject size and can be calculated using the Du Bois formula:
Example
BSA = 1.7 square metres
MAP = 95 mm Hg
RAP = 5 mm Hg
then at a normal resting cardiac output (for an average adult) of 5 l/min
substituting the numbers above this gives an SVR of 1440.
So, in summary
CO = 5
SVR = 1440
CI = 2.9
SVRI =2448
the pressures are the same as above but the patient is smaller with a BSA of 0.85 and a cardiac output of 2.5, then
CO = 2.5
SVR = 2880
CI = 2.9
SVRI =2448